Shut a door, start a conspiracy theory?
Ivan Seeking said:
Yep. What interested me most were questions that don't generate grant money or careers.
Well, call me Dr. Pangloss, but it seems to me that genuine scientific success always generates grants and students, so isn't this simply a lamentation of personal failure to make sufficient scientific progress toward solving your favorite enigma?
Ivan Seeking said:
However, this doesn't mean that those questions should be ignored or forgotten.
We might offer different answers to the question "what are the deepest enigmas in science?", but whatever our respective lists might be, no-one is suggesting that we should collectively ignore/forget deep questions!
Ivan Seeking said:
And I think it is true that orthodoxy can stifle valid discussions of the deepest issues. I once had a physics professor close her door so that she could freely discuss her views on such matters, and I was quite struck by this.
I think you're making too much of that incident. Maybe she realized that with rising passions you and she were disturbing her neighbors?
I have a different interpretation: raising the bar when it comes to revolutionary change by adopting some proposed solution to some fundamental enigma internalizes and intensifies discussion and debate. Those obsessed with their own pet theory "solving" the enigma spend far more time in internal critiques than they might with humdrum science (or else become the butt of a jest by Kibo*). This is a good thing and should be encouraged, since it ensures that when scientifically useful "revolutionary" solutions do emerge, they are accompanied by spectacularly well argued and carefully expressed arguments. Einstein 1905 is a good example, in which overwhelmingly persuasive arguments from a scientific unknown quickly captured the attention and indeed the support of the leaders of physics (well, Planck and friends; those who couldn't make the transition to relativistic physics were unceremoniously deposited in the dustbin of science, which was also a good thing).
*You know, the Guy that Runs the Internet.
I happen to think that as a rule, the best papers are singly authored (is Christine Dantas hereabouts, by any chance?), and if so, this simply reinforces my suspicion that laments about the alleged "discouragement of open discourse" concerning some fundamental enigma reduce upon closer examination to the confession "no Einstein I".
(I assume we are discussing something like the interpretation of QM; if not maybe this is one time when you should
not disabuse me! Also, I stress that I am assuming that we all belong to the group of individuals who have struggled and failed by dint of our own efforts to resolve some deep enigma of science, whatever humdrum successes we may have enjoyed.)
IOW, scientific revolutions, unlike political revolutions, are best accomplished by lone pioneers, in private. After that it is simply a matter of publishing the enunciation of the new marching orders.
To toss another idea into the mix: with the exponential growth of the hierarchical structure of mathematics, which I like to define as the art of reliable reasoning about simple phenomena, and which is the foundation of science, humans are becoming obsolete as the agents of science. Clearly longer-lived and far more intelligent scientists are needed. If they do not exist

they must be invented.
(Some cry COI when I say this.)