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It's not clear to me, what you mean. Are you referring to something like the "unitary gauge"?
Also in the simpler abelian case, where you can use the Gupta-Bleuler formalism, you have "negative-norm states" first but then introduce the constraint conditions for physical states. In the original form of the Gupta-Bleuler formalism there are no FP ghosts introduced. This has been done for QED by Feynman first. Using the FP formalism for abelian gauge fields in the standard covariant gauges, the FP ghosts are non-interacting and thus play no role in the Feynman rules for physical S-matrix elements.
Of course all this is defined (though mathematically not rigorously) within perturbative QFT only.
Also in the simpler abelian case, where you can use the Gupta-Bleuler formalism, you have "negative-norm states" first but then introduce the constraint conditions for physical states. In the original form of the Gupta-Bleuler formalism there are no FP ghosts introduced. This has been done for QED by Feynman first. Using the FP formalism for abelian gauge fields in the standard covariant gauges, the FP ghosts are non-interacting and thus play no role in the Feynman rules for physical S-matrix elements.
Of course all this is defined (though mathematically not rigorously) within perturbative QFT only.