Reversing the limits of an integral results in a change of sign, which reflects the orientation of the area being calculated. Geometrically, this is akin to moving the front end of a region to the back, maintaining the area but altering its orientation. The discussion highlights that while Riemann sums can be considered without orientation when focusing solely on area, orientation becomes crucial in calculus for accurately determining values and understanding the implications of direction. The conversation emphasizes that calculus encompasses both a framework for calculations and a broader analytical approach, underscoring the importance of orientation in mathematical operations. Understanding these concepts is essential for grasping the nuances of calculus and its applications.