How do I synthesize Cedryl Acetate for perfumery?

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SUMMARY

The synthesis of Cedryl Acetate for perfumery involves using cedrol as a precursor, which can be obtained from cedar oil through fractional vacuum distillation. While the process of esterification with acetic acid is straightforward and commonly taught in organic chemistry labs, the discussion highlights the impracticality of synthesizing a compound that costs only a few dollars. Additionally, the acquisition of lab glassware and reagents may attract scrutiny due to their association with controlled substances, making purchasing the compound a more viable option.

PREREQUISITES
  • Understanding of esterification and hydrolysis processes
  • Familiarity with fractional vacuum distillation techniques
  • Knowledge of organic chemistry lab safety and regulations
  • Access to cedrol or cedar oil as starting materials
NEXT STEPS
  • Research the process of esterification with acetic acid
  • Learn about fractional vacuum distillation methods
  • Investigate the regulations surrounding the purchase of lab glassware and chemicals
  • Explore commercial sources for Cedryl Acetate and its applications in perfumery
USEFUL FOR

Perfumers, organic chemists, hobbyists in fragrance synthesis, and anyone interested in the practical aspects of chemical synthesis and lab safety regulations.

krasss
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I wanna synthesize 10 ml of Cedryl Acetate for my perfume. How can i do it?
 
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Why? Isn't that like $1 worth?
 
Vanadium 50 said:
Why? Isn't that like $1 worth?
Not in here...
 
This is simple ester so synthesis is probably rather trivial if you have access to lab glass, but you will still need to buy cedrol - so why not save yourself unnecessary work and buy cedryl acetate instead?
 
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Do you have access to pure cedrol? If not, you will need to obtain cedar oil and perform a fractional vacuum distillation.
There are multiple ways to make acetate esters but since those methods are used to make heroin as well…. you could be scrutinized by who knows? Most of the reagents that are easily obtained are on “diversion” lists and purchases are watched.

Best to just buy some?
 
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chemisttree said:
since those methods are used to make heroin as wel
Oh my.
 
:eek:... Entertaining the gentlemen wearing sport jackets and shoulder holsters is NOT conducive to 'Live Long and Prosper'; regardless of which side they are on!
 
Vanadium 50 said:
Oh my.

While it is definitely true that acylation is used in some drug synthesis procedures, it is a bit like claiming screwdrivers are for repairing guns.

Esterification with acetic acid (and the reverse process, hydrolysis of esters) are between those basic things commonly used in ChemOrg101 labs. Trivial to understand, in many basic cases simple to set up.
 
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  • #10
Whew!

Still, it seems very odd to want to synthesize something that costs a few dollars at most. Heck, the glassware is more expensive!
 
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  • #11
Glassware is on watchlists as well. After leaving my research job at SwRI, I set up a lab from scratch. I was required to label and inventory almost all of my glassware and report it to the Texas Department of Public Safety. A Trooper came out to inspect my lab and paperwork!

Don’t Mess With Texas!
 
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  • #12
chemisttree said:
Don’t Mess With Texas!
Or they may Tread On YOU! :wink:
 
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  • #13
Tom.G said:
Or they may Tread On YOU
I think that's South Carolina.
Or Soviet Russia. :smile:
 
  • #14
You are certainly a lot closer than I was!

I remembered it as a Texas flag with a Rattlesnack and saying "Dont Tread On Me".

However Google/Wikipedia state, among other things, that:
In the United States military, the phrase is the motto of the US Army's oldest infantry regiment, the 3rd U.S. Infantry Regiment (The Old Guard), located at Fort Myer, Virginia. "Don't tread on me" is also used in the First Navy Jack of United States Navy.

(from:
https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=don't+tread+on+me+political+meaning)
 

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