To build an amplification circuit for a 10V, 1.7MHz signal from a signal generator, a high voltage FET amplifier is recommended, as it is cost-effective and reliable. The project aims to amplify the signal to 100V to drive a piezoelectric disk, which may behave like a capacitive load. Safety is crucial when working with high voltage, and the power supply must exceed 100V to effectively drive the load. It's essential to measure the output accurately and consider using an oscilloscope to monitor performance. If building a transformer is challenging, commercially available amplifiers may be a safer alternative.