Living cells not only construct themselves, but as open thermodynamic systems, they must ‘eat’ to survive. In general, cells can evolve to ‘eat’ because living cells are nonlinear, dynamical systems with complex dynamical behaviour that enables living cells, receiving inputs from their environment and acting on that environment, to sense and categorize their worlds, orient to relevant features of their worlds, evaluate these as ‘good or bad for me’ and act based on those evaluations. This is the basis of
agency and meaning. Agency and meaning are immanent in evolving life. The
semantic meaning is: ‘I get to exist for a while’. The capacity to ‘act’ is immanent in the fact that living cells achieve constraint closure and do thermodynamic work to construct themselves. The same capacity enables cells to do thermodynamic work on their environment. A cell’s action is embodied, enacted, embedded, extended and emotive [
40,
42,
43,
52,
53].
Cells are molecular autonomous agents, able to reproduce, do one or more thermodynamic work cycles and make one or more decisions, good or bad for me [
52,
53]. The capacity to learn from the world, categorize it reliably and act reliably may be maximized if the cell, as a nonlinear dynamical system, is dynamically critical, poised at the edge of chaos [
54,
55]. Good evidence now demonstrates that the genetic networks of many eukaryotic cells are critical [
56,
57]. Such networks have many distinct dynamical attractors and basins of attraction. Transition among attractors is one means to ‘make a decision’. It will be of interest to test whether Kantian whole autocatalytic sets can evolve to criticality.