Learning high-level math independently, such as calculus and differential equations, is indeed possible, but it comes with challenges. A solid foundation in precalculus is essential, with recommendations to engage with problem-solving resources like those from the Art of Problem Solving. For those considering a math or physics major, familiarity with real analysis is beneficial, with suggested textbooks including "Baby Rudin" and "An Introduction to Analysis" by William R. Wade. Starting with calculus is crucial, and books like "Calculus Made Easy" by Thompson and Michael Spivak's "Calculus" are recommended over others like James Stewart's. While self-study is feasible, the consensus is that the structured environment of a university, with access to instructors and peers, significantly enhances understanding and motivation. The social dynamics and guided learning provided in academic settings can help mitigate the difficulties of self-teaching complex concepts.