Multiple fusion: daughter cells different from parent cell?

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SUMMARY

In the discussion, participants clarify that multiple fusion results in daughter cells that are genetically identical to the parent cell due to mitosis without cytokinesis. The process discussed is schizogony, a form of asexual reproduction where multiple nuclear divisions occur before cytoplasmic division. The cyclic nature of malaria, caused by the Plasmodium lifecycle, is highlighted, emphasizing the role of Anopheles falciparum in genetic duplication. The confusion between multiple fusion and multiple fission is addressed, confirming that multiple fission does involve cytokinesis, leading to genetically identical daughter cells.

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  • Understanding of mitosis and cytokinesis
  • Familiarity with the Plasmodium lifecycle
  • Knowledge of schizogony and multiple fission
  • Basic concepts of asexual reproduction
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gracy
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I think in Multiple fusion daughter cells are different from parent cell.I interpreted this by looking at the image below
multiple.jpg

Have I interpreted correctly?Is this image reliable?
 
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This process is is called schizogony: mitotic division in which multiple rounds of nuclear divisions occur before the cytoplasm segments. So the resulting cells are all genetically the same.

The only time you have sexual reprduction (and therefore changes in genes) is in the gut of the malaria mosquito (Anopheles falciparum).
This picture helps a lot
https://upload.wikimedia.org/wikipedia/commons/0/0b/Plasmodium_lifecycle_PHIL_3405_lores.jpg

Look at the diagram.
Step 1 happens only when the mosquito injects sporozoites. This starts cycle A in your diagram. A only happens after a mosquito bite.
... -> step 4 is what you are talking about: where the schizont makes genetic duplicates of itself.
Step 4 starts another cycle - labelled B. This is the cycle that is the cause of the cyclic nature of malaria. Short periods of violent illness with an interlude of several days - or maybe weeks.

So malaria kills some liver cells, but repeatedly kills off red blood cells. Marlaria is an extreme problem for millions of people on almost every continent.
Malaria deaths in 2013 were ~580,000 with about 198 million infections: http://www.who.int/features/factfiles/malaria/en/
 
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jim mcnamara said:
Look at the diagram.
Step 1 happens only when the mosquito injects sporozoites. This starts cycle A in your diagram. A only happens after a mosquito bite.
... -> step 4 is what you are talking about: where the schizont makes genetic duplicates of itself.
Step 4 starts another cycle - labelled B. This is the cycle that is the cause of the cyclic nature of malaria. Short periods of violent illness with an interlude of several days - or maybe weeks.
But this does not really answer my question.Please help.
 
What really is your question - the cells are identical after multiple fusion? They are identical genetically.
 
First, there is no fusion going on in the diagram you're showing. The cells containing multiple nuclei result from mitosis without cytokinesis, not from two cells fusing together. Just as in normal mitosis, this process results in identical nuclei but instead of being segregated into different daughter cells, the two identical nuclei remain in the same cell. The process can repeat to create a cell with many identical nuclei. Here's a section from Molecular Biology of the Cell discussing this phenomenon, with a very nice picture of these multinucleate cells during mitosis: http://www.ncbi.nlm.nih.gov/books/NBK26831/#_A3392_

Multinucleated cells can arise from many cells fusing together (see https://en.wikipedia.org/wiki/Syncytium), but this is not the process shown in the diagram.
 
Sorry I meant Multiple fission in the title .
Ygggdrasil said:
The cells containing multiple nuclei result from mitosis without cytokinesis,
And in multiple fission cytokinesis does occur.Right?
 
Multiple fission is a type of asexual reproduction.So,I think daughter cells would be same as mother cell(cell which gives rise to those daughter cells)genetically,.But what about size?
 

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