Nano Engineering for Next-Gen Drug Development

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Discussion Overview

The discussion centers on the application of nanoengineering in the development of next-generation drugs, exploring various technologies and methodologies that utilize nanotechnology in drug delivery and medical applications.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • Some participants mention various technologies in nanoengineering, including dendrimers, liposome capsules, quantum dot imaging techniques, self-assembling peptides, scaffolds for tissue engineering, drug-delivery systems for photodynamic therapy, and hydrogels.
  • It is noted that while many drugs are in testing and development using nanotechnology, doxorubicin is highlighted as the only commercial example currently known.
  • One participant inquires about the potential use of nanoengineering with DNA parts, prompting a discussion on the applications of DNA and RNA in nanotechnology.
  • Another participant emphasizes that siRNA can be integrated with nanoengineered systems for drug delivery, highlighting its potential in gene manipulation and medical applications.

Areas of Agreement / Disagreement

Participants express a variety of viewpoints regarding the technologies and applications of nanoengineering in drug development. There is no consensus on specific methods or the extent of their application, indicating that multiple competing views remain.

Contextual Notes

Limitations include the specificity of applications mentioned, the dependence on definitions of nanotechnology, and the varying levels of commercial availability of the discussed technologies.

Who May Find This Useful

This discussion may be of interest to researchers, students, and professionals in the fields of nanotechnology, pharmacology, and biomedical engineering.

markone
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is there any new technology use NANO engineering to create new generation of drugs ?
 
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Many! (You don't need to capitalise the 'nano' btw), here's a list;

Dendrimirs
http://en.wikipedia.org/wiki/Dendrimer

Liposome capsules (see doxyrubicin http://en.wikipedia.org/wiki/Doxorubicin#Liposomal_formulations)
http://en.wikipedia.org/wiki/Liposome#Applications

Quantum dot imaging techniques
http://en.wikipedia.org/wiki/Quantum_dot

Self-assembling peptides
http://en.wikipedia.org/wiki/Self-assembling_peptide#Present_and_future_applications

Scaffolds for tissue engineering
http://en.wikipedia.org/wiki/Tissue_engineering#Scaffolds

Various drug-delivery systems for photodynamic therapy
http://en.wikipedia.org/wiki/Photodynamic_therapy

Hydrogels (can be used as tissue scaffolds or site-specific drug delivery systems)
http://en.wikipedia.org/wiki/Hydrogels#Hydrogels

And the list goes much further than that. However I should state that whilst there are dozens of drugs that implement some form of nanotechnology in testing and development at the moment doxyrubicin is the only one I know of off the top of my head that is commercial.

Nanomedicine has many areas on which it focuses, here I've tried to give you a list of different methods of drug delivery/imaging. If you were to include medical devices (prosthetics, surgical tools, monitors) or biomedical research equipment (AFM, lab-on-chip, optical tweezers) the list would explode further
 
thank you
i want ask if any way to use NANO engineering to use DNA parts
 
(again you don't have to say 'NANO', the correct term is nanotechnology, nanoengineering or nanomedicine).

There are many applications and much research into using DNA and RNA. Wikipedia has an excellent article.

http://en.wikipedia.org/wiki/DNA_nanotechnology

For RNA whilst it's not strictly nanotechnology siRNA can be used in conjunction with nanoengineered systems (i.e. drug delivery) for a wide variety of research and medical applications. The potential for siRNA treatments is astounding, siRNA works by preventing genes forming proteins. This is a fundamental aspect of molecular biology and the ability to manipulate it is highly desirable

http://en.wikipedia.org/wiki/SiRNA
 

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