Oxidation of Alcohol - Ethanol & Acids in Exposed Alcoholic Drinks

  • Thread starter Thread starter xunxine
  • Start date Start date
  • Tags Tags
    Alcohol Oxidation
Click For Summary

Discussion Overview

The discussion revolves around the oxidation of alcoholic beverages, specifically ethanol, when exposed to air. Participants explore the chemical processes involved, including the potential formation of various acids, the role of enzymes in metabolism, and the implications of these processes for health.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant questions whether oxidation of ethanol leads strictly to ethanoic acid or if other acids, such as propanoic acid, could also be formed, suggesting a need for clarification on the presence of other alcohols.
  • Another participant notes that while other alcohols can be oxidized to different acids, ethanol is typically the most significant component in alcoholic beverages due to its higher concentration.
  • A participant explains that the oxidation of ethyl alcohol to ethanoic acid is straightforward because both contain the same number of carbon atoms, implying that producing propanoic acid would require additional steps.
  • One participant inquires about the oxidation mechanism of ethanol in air, specifically whether it first converts to ethanal (acetaldehyde) before becoming ethanoic acid, expressing curiosity about the chemical process involved.
  • Another participant clarifies that acetaldehyde dehydrogenase is an enzyme that oxidizes acetaldehyde to acetic acid, not a product of ethanol metabolism.
  • There is a discussion about the toxicity of acetaldehyde and its production in relation to ethanol consumption, with some participants expressing confusion over the enzyme's role and presence in the body.
  • One participant acknowledges a misunderstanding regarding the production of acetaldehyde dehydrogenase, suggesting that it is produced in response to ethanol presence rather than being constantly available.
  • Another participant reiterates that acetaldehyde is the toxic compound produced from ethanol metabolism, while alcohol dehydrogenase converts ethanol to acetaldehyde.

Areas of Agreement / Disagreement

Participants express differing views on the oxidation products of ethanol and the role of enzymes in its metabolism. There is no consensus on the specifics of the oxidation process or the implications for health, indicating ongoing debate and uncertainty.

Contextual Notes

Some statements rely on assumptions about the presence of other alcohols and the mechanisms of enzyme action, which are not fully resolved in the discussion. The complexity of the biochemical processes involved is acknowledged but not definitively clarified.

xunxine
Messages
31
Reaction score
0
What happens when alcoholic beverages are left exposed to air?
i read that they are oxidised to ethanoic acid. Strictly only ethanoic acid? Why not say, propanoic acid? Or a mixture of acids possible to be present? Is it because only ethanol is present in alcoholic drinks? If so, only ethanol then?
 
Chemistry news on Phys.org
If there are other alcohols they can be oxidized to other acids/aldehydes, but ethanol is usually the most important component (after water), and it is present in concentration tens if not hundreds times higher than those other alcohols.

--
methods
 
Ethyl alcohol contains 2 carbon atoms. Ethanoic acid contains 2 carbon atoms as well. The oxidation is straightforward. The production of propanoic acid (3 carbons here!) from ethyl alcohol would require the addition of an additional carbon atom... not as straightforward you see.
 
I have a somewhat related question. I know that the liver converts the ethanol into acetaldehyde dehydrogenase, and aldehydes are usually the precursors to carboxylic acids. Is there an intermediate step in the oxidation of ethanol in air, where it is first turned to ethanal (acetaldehyde) and then to ethanoic acid? I'm not claiming to have a comprehensive knowledge of organic chemistry, but I'm curious to know the mechanism behind this.
 
Acetaldehyde dehydrogenase is an enzyme responsible for oxidation of acetaldehyde to acetic acid, not product of ethanol metabolism.

--
 
Alright, that makes sense. But from the reading I've done (given it wasn't exactly unbiased scientific research), acetaldehyde dehydrogenase is highly toxic and is produced in larger amounts when ethanol is consumed, thus the (one of many) reason drinking is harmful. However, I read your post to mean that it isn't produced as a direct result of ethanol consumption, but rather that it is present in constant amounts. I feel like I'm missing something.
 
pzona said:
Alright, that makes sense. But from the reading I've done (given it wasn't exactly unbiased scientific research), acetaldehyde dehydrogenase is highly toxic and is produced in larger amounts when ethanol is consumed, thus the (one of many) reason drinking is harmful. However, I read your post to mean that it isn't produced as a direct result of ethanol consumption, but rather that it is present in constant amounts. I feel like I'm missing something.

Perhaps you're thinking of http://en.wikipedia.org/wiki/Acetaldehyde" ?
 
Last edited by a moderator:
That's what I thought at first. I checked my source (a pamphlet on responsible drinking, published by a volunteer group at Penn State) and it said that acetaldehyde dehydrogenase is produced. I'm guessing this is just a mistake made by people trying to sound scientific.
 
Acetaldehyde dehydrogenase is produced in cell as an answer to the ethanol presence, it doesn't sit there for ever waiting; but it is acetaldehyde it produces that is toxic.

--
methods
 
  • #10
Alright, that makes more sense. Thanks for the replies!
 
  • #11
Borek said:
Acetaldehyde dehydrogenase is produced in cell as an answer to the ethanol presence, it doesn't sit there for ever waiting; but it is acetaldehyde it produces that is toxic.

Perhaps in a round about way this is so. Acetaldehyde dehydrogenase works on acetaldehyde, converting it to acetic acid. But of course the presence of acetaldehyde can be correlated to alcohol consumption.

Alcohol dehydrogenase converts ethanol to acetaldehyde.
 
  • #12
Yep, my mistake :blushing:
 
  • #13
thanks all, for the replies for the alcohol question!
thanks pzona, I'm learning something new too.
 

Similar threads

  • · Replies 2 ·
Replies
2
Views
2K
  • · Replies 6 ·
Replies
6
Views
7K
  • · Replies 16 ·
Replies
16
Views
5K
  • · Replies 5 ·
Replies
5
Views
52K
  • · Replies 6 ·
Replies
6
Views
1K
  • · Replies 21 ·
Replies
21
Views
6K
  • · Replies 2 ·
Replies
2
Views
3K
  • · Replies 15 ·
Replies
15
Views
3K
  • · Replies 1 ·
Replies
1
Views
5K
  • · Replies 7 ·
Replies
7
Views
41K