This problem is quite similar to one that I've published on. However, I would never assume that any three-dimensional system consisting of more than 4 point charges is "uniform". (What is meant by "uniform"?!)
In this case, perhaps we are talking about the original Thomson problem (or, perhaps the jellium model that many today love and adore) in which Thomson assumes that the atom consists of negatively charged electrons (corpuscles) in a "uniform" positively charged volume. But, with our knowledge of atomic structure today, having particulate structure, what does "uniform" mean? With five point charges, one can never place all of them in a three-dimensional volume such that they are all equidistant from each other. At best, you could find a configuration in which they may all have the same electrostatic energy.
..basically, my argument is that this question is physically impossible, not so much because of so-called 'quantum-fluctuations' that prevent a negative point charge charge from actually finding, and residing at, the origin of the sphere, but because there is no such as a perfectly "uniform" volume of charge. ...those charges are particles.
Now, if we are discussing "an approximation to uniformity", then the greater the number of charges there is in the positive sphere, the better that approximation. Then, we might as well consider a metallic system because all the spatial symmetry properties of the "uniformity" must be "washed out".
While this may seem like a trivial point to make, I assure you that it makes a world of difference in the final analysis. Of course, if you're looking for a statistical-natured argument (e.g. quantum or density functional), then by all means, this is a trivial point. But if you're looking for a true electrostatic solution, then this point is of utmost importance.
Just some thoughts.
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