Prepare a 100mg/ml solution of glacial acetic acid in methanol

How to prepare a 100mg/ml solution of glacial acetic acid in methanol? The density of glacial acetic acid is 1.05 g/cm^3.

symbolipoint
Homework Helper
Gold Member
Measure the acetic acid with a pipet and prepare the solution in a volumetric flask.

OK, so let me see if I understand you correctly.

Because my acetic acid is a liquid, I would weigh out (on a scale) 100 mg of acetic acid into a volumetric flask and then dilute to 1 ml with methanol. Is this correct?

And if I had to prepare 10 ml having a concentration of 100 mg/ml, I would just multiply whatever it was that I weighed out for the 1 ml solution by 10, right?

Now what happens if the desired concentration is just too small to weigh out...How would you calculate the volume needed arithmetically?

symbolipoint
Homework Helper
Gold Member
You would have too much trouble weighing the precise amount of acetic acid that you would want. Use VOLUME with a pipet. You have the density of your acetic acid, so just calculate how much volume you need for the amount of final solution that you want.

You may think in this way:
Find how much volume acetic acid needed for 1 ml.
Now, how much volume acetic acid do you need for your target ml. of final solution?
In other words, how much larger is your target solution than 1 ml? This is how many times more acetic acid material you need to pipet.

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