Reverse Translation: Could DNA be Synthesized?

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SUMMARY

The discussion centers around the feasibility of synthesizing DNA from amino acid sequences, sparked by an April Fools' article. Participants highlight the complexities of translating mRNA into proteins, emphasizing the role of codons and tRNA in this process. The conversation also touches on the challenges of determining specific triplets from an amino acid sequence, particularly due to the wobble hypothesis. Ultimately, the consensus is that direct conversion of DNA to proteins is not straightforward.

PREREQUISITES
  • Understanding of mRNA and its role in protein synthesis
  • Knowledge of codons and their function in translation
  • Familiarity with tRNA and its interaction with amino acids
  • Concept of wobble base pairing in genetic coding
NEXT STEPS
  • Research the process of mRNA translation and the role of codons
  • Study the wobble hypothesis and its implications in genetic coding
  • Explore the mechanisms of tRNA and its interaction with ribosomes
  • Investigate the theoretical frameworks for synthesizing DNA from proteins
USEFUL FOR

Biologists, geneticists, and anyone interested in molecular biology and the complexities of protein synthesis.

Suraj M
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Is this a true phenomenon??
I just read 1 article, but i don't believe it
Could DNA really be synthesized using The amino acid sequence?
 
Biology news on Phys.org
From the bottom of your link:

UPDATE: (April 2) too many people thought this was serious. Please check the date of this post. Then look up if there is even a Franklin National Lab or an A. lupicus. Then chill out.

It's an April fools. To address the point of if its possible though I'll give you something to think about: how is mRNA read so that proteins might be translated (hint: look into codons).
 
Ryan_m_b said:
how is mRNA read so that proteins might be translated
tRNA.. nodoc or anticodon reads the Triplets of RNA and the CCA (3') end attaches to the Amino acid bringing it for protein synthesis.. so?
 
Yup you have the triplets, and if you were to have the amino acid sequence could you figure out the specific triplet?
 
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Likes   Reactions: Hamza Qureshi
ahh.. there lies the problem. :redface:
wobble! Thank you! actually this was a part of a question, is it ok if i mentioned the question here, because it might be against the rules..i might have a follow up question..
 
May I?
is it possible to convert DNA directly to proteins?
 

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