Reverse Translation: Could DNA be Synthesized?

AI Thread Summary
The discussion centers around the feasibility of synthesizing DNA from an amino acid sequence, sparked by an article that turned out to be an April Fools' joke. Participants emphasize the importance of understanding how mRNA is translated into proteins, specifically through the role of codons and tRNA. The challenge lies in determining the specific triplet codons from an amino acid sequence due to the redundancy in genetic coding, known as the "wobble" effect. A question is raised about the possibility of directly converting DNA to proteins, indicating further inquiry into the topic.
Suraj M
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Is this a true phenomenon??
I just read 1 article, but i don't believe it
Could DNA really be synthesized using The amino acid sequence?
 
Biology news on Phys.org
From the bottom of your link:

UPDATE: (April 2) too many people thought this was serious. Please check the date of this post. Then look up if there is even a Franklin National Lab or an A. lupicus. Then chill out.

It's an April fools. To address the point of if its possible though I'll give you something to think about: how is mRNA read so that proteins might be translated (hint: look into codons).
 
Ryan_m_b said:
how is mRNA read so that proteins might be translated
tRNA.. nodoc or anticodon reads the Triplets of RNA and the CCA (3') end attaches to the Amino acid bringing it for protein synthesis.. so?
 
Yup you have the triplets, and if you were to have the amino acid sequence could you figure out the specific triplet?
 
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Likes Hamza Qureshi
ahh.. there lies the problem. :redface:
wobble! Thank you! actually this was a part of a question, is it ok if i mentioned the question here, because it might be against the rules..i might have a follow up question..
 
May I?
is it possible to convert DNA directly to proteins?
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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