In the real world, you may see the path of a ray of light (consisting of many photons) because the light is scattered from dust and air molecules. Generally this scattering will redirect the light in all directions, including your eye, and what you see is the volume of space the light is scattered from. It would be hard to see a single photon in the real world as that would be scattered in one particular direction that would likely miss your eye, and besides it would just be a single blip of light. In your hypothetical empty space, there would be nothing to scatter or redirect the light to your eye so it would not be visible.