What Does the Negative Sign in the Electrostatic Potential V Formula Represent?

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Potential at a position is defined as the Work Done in bringing a charge (or whatever) from infinity to that position. For an attractive situation (+ and - charges, for instance), the work 'put in' is negative, because you get work out. For a negative charge around an atom or a small mass near a large one, you can look upon it as being in a 'potential well', with the potential at a minimum if and when they 'land'. You can only leave the influence of the attractor if you have more kinetic energy (positive) than the negative potential energy due to position.