..disagreement continues between philosophers over whether it is itself an entity, a relationship between entities, or part of a conceptual framework.
That kind of sums things up.
Science mostly explains how things behave as we observe. So you can ask "What is space?" or What is time? or an electron or...on and on and science has no real good answers.
I would say space IS physical...[but as noted that depends on just what one means] or has physical effects else, why does a distant 'house' look small and a nearby house look 'big'. We can only stuff so many cans in a box, so many atoms in a material, and so forth. So it seems space does have physical effects and as explained by the theory of special relativity, intertwines with time in such a way that as relative speed changes, so does space and time. Space and time are not unchanging and fixed as they appear in everyday slow speed life.
There is not even firm agreement among scientists whether space is continuous,meaning smooth even at the tiniest scales, or discrete, meaning whether it comes in tiny lengths. Relativity is a theory of continuous and quantum theory, discrete. Both work well, but not at the tiniest length scales, called Planck length.
A pair of explanations I find insightful:
Time is what keeps everything from happening at once.
Space is what keeps everything from happening to me.