Medical Why do we say basolateral membrane and not basal?

AI Thread Summary
The discussion centers on the terminology used to describe the basolateral membrane in kidney physiology. The term "basolateral" is preferred over "basal" because it encompasses both the basal and lateral aspects of the membrane, which are crucial for the cell's function in substance transfer. This distinction is significant in epithelial cells, where the apical and basal sides have different roles. The lateral membranes enhance the surface area for transport processes, making the term "basolateral" more descriptive of the membrane's functional characteristics. Understanding this terminology is essential for accurately discussing kidney physiology and cellular function.
red65
Messages
13
Reaction score
0
Hello everyone, I am studying the physiology of the kidneys and in all of the textbooks they say basolateral membrane referring to the basal membrane, does anyone know why we don't just say basal membrane?
 
Biology news on Phys.org
Depending on the structure of the membrane you are talking about, basolateral might be referring to parts of the cell with the same function (transferring stuff across a membrane, which is what the kidney does a lot of). If that were the case the lateral membranes would provide an increase in surface area through which transfers could occur. If so, this would be a functional issue influencing the name used.

In general, there is a cytological distinction in many animal cells between the apical and basal sides of the cell. All epithelial cells have this distinction.
 
  • Like
  • Informative
Likes jim mcnamara, pinball1970 and berkeman
  • Like
  • Informative
Likes red65, BillTre, jim mcnamara and 1 other person
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
Back
Top