Why don't humans regrow lost limbs?

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SUMMARY

The discussion centers on the impossibility of humans regrowing lost limbs, contrasting human biology with that of species like newts and salamanders that can regenerate. Key points include the complexity of embryonic development, which occurs within the first eight weeks of gestation, and the crucial role of gene expression and morphogenetic fields in limb formation. Current advancements in regenerative medicine, such as products from ACell Inc and LifeCell, aim to stimulate regeneration but do not replicate the full limb growth process. The consensus is that while prosthetic technology may advance, the biological regrowth of limbs in humans remains unlikely due to the inherent differences in adult and embryonic cellular contexts.

PREREQUISITES
  • Understanding of embryonic development stages and gene expression
  • Knowledge of regenerative medicine and current technologies
  • Familiarity with the concept of morphogenetic fields
  • Awareness of the differences between adult and fetal stem cells
NEXT STEPS
  • Research the mechanisms of gene therapy and its applications in regenerative medicine
  • Explore the advancements in prosthetic technology and neural integration
  • Study the role of morphogenetic fields in developmental biology
  • Investigate the regenerative capabilities of various species and their genetic underpinnings
USEFUL FOR

This discussion is beneficial for biologists, medical researchers, and bioengineers interested in regenerative medicine, prosthetics, and the biological limitations of human limb regeneration.

  • #31
Ruslan_Sharipov said:
So, nowadays, lost limbs can be reconstructed without any genomics and stem cells.

Remember, we are not talking about reconstructing something that LOOKS like a limb, we are talking about reconstructing something that SERVES as a limb.
 
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  • #32
If you reconstruct bones, and muscles, and blood vessels, and nerves, and joints, and skin,
then your item LOOKING like a limb will SERVE as a limb.
 
  • #33
Ruslan_Sharipov said:
If you reconstruct bones, and muscles, and blood vessels, and nerves, and joints, and skin, then your item LOOKING like a limb will SERVE as a limb.

Ruslan_Sharipov said:
So, nowadays, lost limbs can be reconstructed without any genomics and stem cells.

Do you have any evidence to support a claim that it is currently possible?
 
  • #34
Borek said:
Do you have any evidence to support a claim that it is currently possible?

No, I have not. But I am looking for the opportunity to prove that it is possible in a way I have described in rough details!
 
  • #35
I believe that it is possible and with time will be done as the progress that Mankind is making is exponential and the fact that it already happens in other animals even though they are quite different from us proves that amazing regeneration is possible.
 
  • #36
(there seems to be a problem as my last post seems to disappear unless I send another after it!)

I believe that it is possible and with time will be done as the progress that Mankind is making is exponential and the fact that it already happens in other animals even though they are quite different from us proves that amazing regeneration is possible.
 

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