There is this idea that you often see that He3 makes fusion energy much more attractive, because the D-He3 reaction generates only charged particles and no neutrons, and therefore generates no radioactivity. This is false, because a D-He3 plasma would also generate D-D reactions, which do generate neutrons, as well as generate T, which fuses with D to generate even more neutrons. Also, the D-He3 reaction has a smaller cross-section than the D-T reaction, meaning that D-He3 fusion is harder to intiate than D-T fusion, which we have not yet managed to make practical despite decades of trying. In addition, mining lunar rocks for their tiny fraction of He3 would be a huge undertaking. So the idea that we will go to the moon, pick up some He3 which is lying around, and fusion will then be this wonderful energy source that will save the world and allow us to build fusion rockets is just what you said, "a mashup of Sci-Fi ideas".