There exists such a frame in which the vector sum of the momenta of all the particles is zero. If the ith particle has mass mi and velocity vi, then let v = ∑mivi/∑mi. A frame of reference traveling at this velocity v wrt the lab frame would be such a frame.
For more convenience, you can consider it to be the non-rotating frame with origin at the centre of mass of the whole system and traveling at v.
The total momentum in this frame is zero both before and after a collision.