Is haemosiderin always haemoglobin derived?

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Haemosiderin is defined as a pigment resulting from local or systemic excess iron. The discussion centers on whether excess iron alone can lead to haemosiderin synthesis without the involvement of macrophages breaking down hemoglobin. Clarification is sought regarding the relationship between excess iron and haemosiderin production, indicating a need for a clearer understanding of the mechanisms involved in haemosiderin formation.
sameeralord
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Hello everyone,

Haemosiderin definition says that it is a pigment that occurs when there is a local or systemic excess of iron. Does that mean excess iron deposition can cause haemosiderin pigment, I mean you don't alway need macrophages to eat Hb and make it, just iron is enough. Thanks :smile:
 
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Just to clarify are you asking if excess iron is the cause of haemosiderin synthesis? I don't find your post clear to understand.
 
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