- #1
PoisonCupcake
- 6
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Hi! Was hoping I could get someone to explain this question to me..having some trouble with it...
"At each origin of replication, DNA synthesis proceeds bidirectionally from two replication forks. Which of the following would happen if a mutant arose having only one functional fork per replication bubble?
a.No change at all in replication
b. Replication would take place only on one half of the chromosome
c. Replication would be complete only on the leading strand
d. replication would take twice as long"
The answer is d, which definitely makes sense to me if this was prokaryotic DNA (ie. circular).. but I don't understand how the entire chromosome could be replicated if this was linear DNA like in most eukaryotes. Wouldn't only half of each parental strand be replicated since, for example, there isn't even a replisome traveling in the other direction to get rid of hydrogen bonds?
Thanks for your input in advance :)
"At each origin of replication, DNA synthesis proceeds bidirectionally from two replication forks. Which of the following would happen if a mutant arose having only one functional fork per replication bubble?
a.No change at all in replication
b. Replication would take place only on one half of the chromosome
c. Replication would be complete only on the leading strand
d. replication would take twice as long"
The answer is d, which definitely makes sense to me if this was prokaryotic DNA (ie. circular).. but I don't understand how the entire chromosome could be replicated if this was linear DNA like in most eukaryotes. Wouldn't only half of each parental strand be replicated since, for example, there isn't even a replisome traveling in the other direction to get rid of hydrogen bonds?
Thanks for your input in advance :)