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SW VandeCarr
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Mild cognitive impairment (MCI) may be slowed with B vitamin supplements according to a recent UK study. Other studies have shown that elevated blood homocysteine levels are associated with MCI and more severe cognitive dysfunction including Alzheimer's disease. B12, B6 and folic acid are known to reduce blood homocysteine levels. 271 elderly subjects with MCI were enrolled in this randomized placebo controlled trial and 168 had a final MRI to evaluate brain shrinkage, the main outcome measure in the trial. The study showed a statistically and clinically significant slowing of brain shrinkage in the group treated with high daily doses of B vitamins for two years vs placebo.
http://www.ox.ac.uk/media/news_stories/2010/100909.html
http://www.ox.ac.uk/media/news_stories/2010/100909.html
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