Antibodies against hormones of the own body

In summary, antibodies against hormones of the own body are immune proteins that target and neutralize hormones produced by the body. These antibodies can cause autoimmune disorders, where the body's immune system mistakenly attacks its own tissues and organs. They can also interfere with the body's normal hormone function, leading to hormonal imbalances and health issues. Understanding the role of antibodies in hormone regulation is crucial for managing and treating various diseases and disorders related to hormone production.
  • #1
DrDu
Science Advisor
6,357
974
Recently I came upon the description of medical tests for hormones like cortisole, or tyroid hormones like T3 and T4, which use polyclonal antibodies from hamsters, pigs, sheep or thelike.
As far as I know, they are obtained by vacunating these animals and harvesting the antibodies from their blood. But how can you induce an organism to produce antibodies against hormones it uses itself and needs for its wellbeing?
 
Biology news on Phys.org
  • #3
Thank you, that's very interesting.
 

1. What are antibodies against hormones of the own body?

Antibodies against hormones of the own body are proteins produced by the immune system that recognize and bind to hormones produced by the body. These antibodies are part of the body's defense mechanism against foreign substances and play a role in regulating hormone levels.

2. Why does the body produce antibodies against its own hormones?

In some cases, the immune system may mistakenly identify hormones produced by the body as foreign and produce antibodies against them. This can lead to autoimmune disorders, where the immune system attacks and damages the body's own tissues.

3. What are the consequences of having antibodies against hormones of the own body?

The consequences of having antibodies against hormones of the own body can vary depending on the specific hormone and the individual's immune response. In some cases, it may lead to hormonal imbalances and symptoms such as fatigue, weight changes, and mood swings. In more severe cases, it can result in autoimmune diseases such as type 1 diabetes or Hashimoto's thyroiditis.

4. How are antibodies against hormones of the own body detected?

Antibodies against hormones of the own body can be detected through blood tests, which measure the levels of specific antibodies in the blood. These tests can help diagnose autoimmune disorders and monitor their progression.

5. Can antibodies against hormones of the own body be treated?

Currently, there is no cure for autoimmune disorders caused by antibodies against hormones of the own body. However, treatments such as hormone replacement therapy, immunosuppressive drugs, and lifestyle changes can help manage symptoms and slow the progression of the disease.

Similar threads

  • General Discussion
Replies
11
Views
25K
Back
Top