DNA testing, what kind of sample is the minimum?

In summary, it is possible to conduct a DNA test from fallen hair or skin cells, as even dead cells still retain a unique "fingerprint". This technique is widely used in forensics, with a theoretical limit of detecting just one molecule containing a specific nucleotide sequence. However, the sensitivity of this method can also be a practical challenge, as it can detect very small amounts of DNA and lead to disputes in forensic cases. Further information on this topic can be found by researching "Low copy number DNA".
  • #1
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Is it possible to do DNA test from fallen hair, or skin cells? Or no, since the cells die and lose their core before they fall from the body?
Do dead cells still have somekind of unique "fingerprint"?
 
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  • #2
Yes, and this is widely used in forensics just for traces of DNA also on quite old samples.The theoretical limit is just one molecule containing a given nucleotide sequence. For the practical limit somebody more up-to-date than me will no doubt come and tell you.

Often the practical problem will come not from the limitation of sensitivity, but from the very great sensitivity itself! Almost too much can be detected. A given DNA sequence will often be just one amidst dozens or hundreds of others in a sample. In the case of criminal forensics you can pick up an extremely tiny amount of DNA and establish that it almost certainly came from a certain person. But how did that tiny amount get to a crime scene? Might be all sorts of indirect and innocent ways. So you get into forensic dispute. For some more information you could google ‘Low copy number DNA’.

Big subject, interesting, somewhat complicated, implications have been and probably still are controversial. (Also because whenever you mention DNA or genetics many people just go bonkers.)
 
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1. What is DNA testing and how does it work?

DNA testing is a scientific method used to identify and analyze the genetic makeup of an organism. This is done by extracting DNA from a sample and then amplifying and analyzing specific segments of the DNA to determine genetic information.

2. What kind of samples can be used for DNA testing?

The most commonly used samples for DNA testing are blood, saliva, and hair. However, other types of samples such as skin cells, semen, and even old toothbrushes can also be used.

3. What is the minimum amount of sample required for DNA testing?

The minimum amount of sample required for DNA testing depends on the type of sample and the testing method being used. Generally, a few milliliters of blood or saliva is enough for most DNA testing methods.

4. Can DNA testing be done on a deceased individual?

Yes, DNA testing can be done on a deceased individual by using samples such as bones, teeth, or hair follicles. However, the quality and quantity of DNA in these samples may vary, which could affect the accuracy of the test results.

5. How accurate is DNA testing?

DNA testing is highly accurate, with a 99.9% chance of providing correct results. However, the accuracy of the test may be affected by sample quality, contamination, or human error during the testing process.

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