Experimental spinal cord implant helps Parkinson’s patient walk in new study

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This is very cool...

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CNN

Marc Gauthier can now step into an elevator without his body stiffening and freezing in place. He can take a 3-mile lakeside stroll without stopping. He can stand up out of a chair with ease. For Gauthier, 63, who has been living with Parkinson’s disease for almost three decades, these everyday activities were a challenge — until now.

“Walking in a store would be really difficult, impossible before, because of the freezing of gait that would often happen in those environments. And now, it just doesn’t happen anymore. I don’t have freezing anymore,” Gauthier, who lives near Bordeaux, France, said in a news briefing, speaking in French that was translated to English.

In a new study, Gauthier was surgically implanted with an experimental spinal cord neuroprosthesis to correct walking disorders in people with Parkinson’s disease. Step by step, he said, it has helped him get his stride back.

The study, published Monday in the journal Nature Medicine, details how the neuroprosthesis works by targeting specific areas of the spinal cord with electrical stimulation that are associated with walking.

“Addressing deficits of gait and balance in Parkinson’s disease is extremely challenging. These deficits can be very heterogenous. They can be variable across patients. They can affect walking but also symmetry, balance, posture,” Dr. Eduardo Moraud, an author of the study and researcher at Lausanne University Hospital in Switzerland said during the news briefing.

“The neuroprosthetic approach that we have developed here allows for the first time to target and address these problems individually in a highly specific manner for each patient,” Moraud said. “It operates in real time, and importantly, it is complementary to other existing therapies.”

https://www.cnn.com/2023/11/06/health/parkinsons-spinal-cord-implant-study/index.html
 
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Remarkable step forward!
 
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Lnewqban said:
Remarkable step forward!
I see what you did there... :wink:
 
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berkeman said:
I see what you did there... :wink:
But seriously, it is impressive that the spinal cord is slowly coming out of that old idea of definitive damage for life.
Thank you for sharing this article; I had no idea.
 
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Agreed. I need to read more about this -- spinal cord repair after paralyzing injury has long been an interest of mine, but this almost sounds like a minimally-invasive stimulation/synchronization of some sort. Off for more reading...
 
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1. What is the experimental spinal cord implant and how does it work?

The experimental spinal cord implant is a device designed to stimulate specific regions of the spinal cord. It works by delivering electrical impulses to areas that control motor functions which are typically impaired in Parkinson’s disease. These impulses can help to improve mobility and coordination, potentially allowing patients to regain abilities such as walking.

2. Who conducted the study and where was it done?

The study was conducted by a team of researchers from a collaboration of various neuroscientific research institutions. The specific details about the institutions involved and the location of the study are typically provided in the full research paper or press release from the conducting body.

3. What were the results of the study?

The study showed promising results where the patient with the spinal cord implant experienced significant improvements in walking abilities. The patient was able to walk with more stability and coordination, which was not possible before the implantation. These results are preliminary but suggest potential benefits of spinal stimulation in managing Parkinson’s disease symptoms.

4. Are there any risks or side effects associated with the spinal cord implant?

As with any medical procedure, especially involving implants and electrical stimulation, there are potential risks and side effects. These can include infection, pain at the implant site, unintended neurological effects, and device malfunction. However, the specific risks associated with this experimental implant will be detailed in the clinical study reports and are closely monitored throughout the trial phases.

5. What does this mean for the future treatment of Parkinson’s disease?

This breakthrough indicates a potential new treatment avenue for Parkinson’s disease, particularly for patients who do not respond well to existing treatments. While more extensive clinical trials are needed to fully understand the efficacy and safety of the implant, this approach could lead to more personalized and effective management of Parkinson’s disease symptoms, improving the quality of life for many patients.

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