How many amino acid residues are there for the transmembrane domain?

Your summary effectively explains the calculation used to determine the number of amino acid residues in the transmembrane domain of the protein.
  • #1
TytoAlba95
132
19
Homework Statement
The rise per residue of an alpaha helix is 1.5 Angstrom. A protein spans 4nm bilayer 7 times, through its transmenbrane alpha-helical domain.Aprroximately how many amino acid residues constitute the transmembrane domain of the protein
Relevant Equations
a) 105
b) 450
c) 30
d)190

Ans:d
Total no. of amino acid in each transmembrane domain = 4 nm/ 0.15 nm +1 =27.66
Total no. of amino acids in 7 transmembrane domains = 27.66 x 7 = 193.62 ≈ 190

Hence option d.

Is my approach correct?
 
Physics news on Phys.org
  • #2
SanjuktaGhosh said:
Problem Statement: The rise per residue of an alpaha helix is 1.5 Angstrom. A protein spans 4nm bilayer 7 times, through its transmenbrane alpha-helical domain.Aprroximately how many amino acid residues constitute the transmembrane domain of the protein
Relevant Equations: a) 105
b) 450
c) 30
d)190

Ans:d

Total no. of amino acid in each transmembrane domain = 4 nm/ 0.15 nm +1 =27.66
Total no. of amino acids in 7 transmembrane domains = 27.66 x 7 = 193.62 ≈ 190

Hence option d.

Is my approach correct?

Yes, that looks correct to me.
 
  • Like
Likes TytoAlba95

1. How many amino acid residues are typically found in a transmembrane domain?

The number of amino acid residues in a transmembrane domain can vary, but on average, it ranges from 20-30 amino acids.

2. Are there any specific amino acid residues that are more commonly found in transmembrane domains?

Yes, hydrophobic amino acids such as leucine, isoleucine, and valine are typically found in transmembrane domains due to their ability to interact with the hydrophobic lipid bilayer of the cell membrane.

3. Can the number of amino acid residues in a transmembrane domain affect its function?

Yes, the length of a transmembrane domain can play a role in its function. Longer domains may provide more stability and support for the protein, while shorter domains may allow for more flexibility and movement.

4. Are there any tools or methods available to predict the number of amino acid residues in a transmembrane domain?

Yes, there are various computational tools and algorithms that can predict the presence and location of transmembrane domains in a protein sequence. These tools use a combination of hydrophobicity analysis, machine learning, and statistical models to make predictions.

5. Can the number of amino acid residues in a transmembrane domain vary between different species?

Yes, the number of amino acid residues in a transmembrane domain can vary between different species and even within the same protein family. This can be due to differences in the structure and composition of cell membranes, as well as the specific functions of the protein in different organisms.

Similar threads

  • Biology and Chemistry Homework Help
Replies
1
Views
2K
  • Biology and Chemistry Homework Help
Replies
2
Views
12K
  • Biology and Chemistry Homework Help
Replies
4
Views
2K
Replies
4
Views
903
  • Biology and Medical
Replies
3
Views
2K
  • Precalculus Mathematics Homework Help
Replies
23
Views
612
  • Biology and Chemistry Homework Help
Replies
4
Views
2K
  • Biology and Chemistry Homework Help
Replies
1
Views
1K
  • Biology and Chemistry Homework Help
Replies
2
Views
8K
  • Biology and Chemistry Homework Help
Replies
3
Views
15K
Back
Top