"Mind-controlled" gene expression

In summary, the conversation discusses a study in which a brain-computer interface (BCI) interprets brain waves to control the expression of a human glycoprotein through a wireless-powered optogenetic implant. The BCI uses an engineered NIR light-activated bacterial diguanylate cyclase (DGCL) to trigger the production of synthetic interferon-β promoters, allowing humans to control the production of the designer cells through different mental states such as biofeedback control, concentration, and meditation. This study suggests that in the future, our thoughts may have the power to control our physical actions.
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Pythagorean
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Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant.

Kind of a sensationalized title, since it's really just interpreting brain waves through a BCI, but neat anyway.

An electroencephalography (EEG)-based brain–computer interface (BCI) processing mental state-specific brain waves programs an inductively linked wireless-powered optogenetic implant containing designer cells engineered for near-infrared (NIR) light-adjustable expression of the human glycoprotein SEAP (secreted alkaline phosphatase). The synthetic optogenetic signalling pathway interfacing the BCI with target gene expression consists of an engineered NIR light-activated bacterial diguanylate cyclase (DGCL) producing the orthogonal second messenger cyclic diguanosine monophosphate (c-di-GMP), which triggers the stimulator of interferon genes (STING)-dependent induction of synthetic interferon-β promoters. Humans generating different mental states (biofeedback control, concentration, meditation) can differentially control SEAP production of the designer cells in culture and of subcutaneous wireless-powered optogenetic implants in mice.

http://www.nature.com/ncomms/2014/141111/ncomms6392/full/ncomms6392.html
 
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Sometime soon you are what you think.
 
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1. What is "mind-controlled" gene expression?

"Mind-controlled" gene expression refers to the ability to manipulate gene expression in response to brain activity or mental states. This is achieved through the use of genetic engineering techniques that allow for the control of specific genes in response to external stimuli or internal brain signals.

2. How is "mind-controlled" gene expression achieved?

The most common method for achieving "mind-controlled" gene expression is through the use of optogenetics, which involves the insertion of light-sensitive proteins into cells to control their function. These proteins can then be activated by specific wavelengths of light, allowing for the precise control of gene expression.

3. What are the potential applications of "mind-controlled" gene expression?

There are many potential applications for "mind-controlled" gene expression, including the treatment of neurological disorders, such as Parkinson's disease or epilepsy, through targeted gene therapy. It could also be used in research to better understand brain function and behavior.

4. Is "mind-controlled" gene expression ethical?

As with any new technology, there are ethical considerations that must be taken into account when using "mind-controlled" gene expression. This includes ensuring informed consent from participants and addressing potential concerns about privacy and the potential misuse of this technology.

5. What are the current limitations of "mind-controlled" gene expression?

While "mind-controlled" gene expression shows great promise, there are still many limitations that need to be addressed. These include the need for more research to fully understand the mechanisms of gene expression control and the potential risks and side effects of using this technology.

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