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The Nobel prize in chemistry for 2016 has been awarded "for the design and synthesis of molecular machines."
These are fascinating constructions made up of just a few molecules, so they are the smallest machines possible. It is far from trivial to get these things working, especially since thermal noise is important at that scale (although in some cases, thermal noise can be rectified and serve as a source of energy).
The popular scientific description can be found here: http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2016/popular-chemistryprize2016.pdf
For a more in-depth description: http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2016/advanced-chemistryprize2016.pdf
P.-S.: As always, Nature had beaten us to it, as there are molecules in living organisms that are basically molecular motors. The most striking example is kinesin, the "walking" molecule fueled by ATP:
These are fascinating constructions made up of just a few molecules, so they are the smallest machines possible. It is far from trivial to get these things working, especially since thermal noise is important at that scale (although in some cases, thermal noise can be rectified and serve as a source of energy).
The popular scientific description can be found here: http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2016/popular-chemistryprize2016.pdf
For a more in-depth description: http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2016/advanced-chemistryprize2016.pdf
P.-S.: As always, Nature had beaten us to it, as there are molecules in living organisms that are basically molecular motors. The most striking example is kinesin, the "walking" molecule fueled by ATP: