Can Pyruvate Supplementation Re-energize the Aging Human Brain?

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In summary, a study found that supplementing aging mice with pyruvate increased their energy reserves and made them more active. However, the reliability of the research is questioned due to the publisher's reputation as a predatory open-access publisher. Therefore, it is advised to wait for the study to be published in a peer-reviewed journal before drawing any conclusions or considering trialing it on humans.
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wolram
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https://www.sciencedaily.com/releases/2016/03/160316194205.htm
Supplementation with the molecule pyruvate increases the energy reserves in the brain of aging mice, and makes them more energetic and keener to explore their surroundings.

Should this be trialed on humans?
 
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I haven't read the paper associated with the press release, but it's worth noting that the publisher of the article (Frontiers) is on Beall's list of predatory open-access publishers (https://scholarlyoa.com/publishers/).
 
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What @Ygggdrasil is implying: the paper could well be just plain wrong. It probably was not peer reviewed.

And this is hard for non-Science people. And Science people from outside the discipline have problems as well: You read a paper in a journal. It looks okay to you and me. But the chance of us being duped is high because of one fact - the publisher - so we have to say 'Whoa. Maybe not.'

Ugh. (IMO).
 
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I think with this information we should close the thread to prevent someone wandering in with misinformation. Until it is published in an accepted peer reviewed journal we will have to sit on the fence on this.
 
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1. How does physical exercise impact brain function in older adults?

Physical exercise has been shown to have numerous benefits for the aging brain. It can increase blood flow to the brain, which helps to nourish brain cells and keep them functioning optimally. Exercise also stimulates the release of chemicals in the brain, such as dopamine and serotonin, which can improve mood and cognitive function. In addition, regular physical exercise has been linked to a decrease in the risk of developing age-related cognitive decline and dementia.

2. Can mental activities help to re-energize the aging brain?

Yes, engaging in mentally stimulating activities can help to re-energize the aging brain. These activities can include puzzles, brain teasers, learning a new language or instrument, and engaging in social interactions. By challenging the brain with new and varied activities, it can help to strengthen existing neural connections and create new ones, which can improve cognitive function and overall brain health.

3. Are there any dietary changes that can improve brain function in older adults?

Research has shown that maintaining a healthy and balanced diet can positively impact brain function in older adults. This includes eating a variety of fruits, vegetables, whole grains, and lean proteins. Omega-3 fatty acids, found in foods like fish and nuts, have also been linked to improved brain health. Additionally, reducing the intake of processed and high-fat foods can help to protect against cognitive decline.

4. Can stress management techniques benefit the aging brain?

Chronic stress has been linked to negative impacts on brain health, including memory loss and cognitive decline. Therefore, practicing stress management techniques, such as meditation, deep breathing, and yoga, can help to reduce stress levels and improve overall brain function. These techniques can also promote relaxation and improve sleep, which are important for brain health.

5. Is it possible to re-energize the aging brain through social interactions?

Yes, social interactions have been shown to have a positive impact on the aging brain. Engaging in social activities, such as spending time with friends and family, joining clubs or groups, and volunteering, can help to stimulate the brain and improve cognitive function. Social interactions also provide a sense of purpose and belonging, which can contribute to overall brain health and well-being.

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