- #1
- 4,770
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- TL;DR Summary
- Thapsigargin therapy is very effective antiviral, per this note.
Research note:
https://nottingham-repository.worktribe.com/output/5270247
Popular science note:
https://scitechdaily.com/powerful-a...-that-could-change-how-epidemics-are-managed/
The research note was hard to get to because there seems to be a copyright embargo1 on the primary paper in the journal "Viruses". Which I could not see, obviously.
The claim is that thapsigargin is effective at reducing viral replication - several virus types including Coronaviruses. Covid-19 is a Coronavirus and seems to be effected as well. This is not a case study, it uses animal models - my assumption.
Thapsigargin is a topic of a large number of other papers discussing properties of the compound - mostly biomedical.
A search in Google Scholar 'thapsigargin' will present with loads options for each flavor of secondary criterion. The point is the compound has lots of reports of interesting properties, which reduces the chances of this research note being a complete anomaly.
I would file it under the 'I hope that some day this has proven merit' section.
1 Copyright embargo: https://en.wikipedia.org/wiki/Embargo_(academic_publishing)
If anyone can see the original, please correct anything that I managed to mess up above.
-- truly unhelpful in this case. It limits what we can reasonably get from either article, although the pop sci article has hyperbole, IMO. Which you should probably ignore.
https://nottingham-repository.worktribe.com/output/5270247
Popular science note:
https://scitechdaily.com/powerful-a...-that-could-change-how-epidemics-are-managed/
The research note was hard to get to because there seems to be a copyright embargo1 on the primary paper in the journal "Viruses". Which I could not see, obviously.
The claim is that thapsigargin is effective at reducing viral replication - several virus types including Coronaviruses. Covid-19 is a Coronavirus and seems to be effected as well. This is not a case study, it uses animal models - my assumption.
Thapsigargin is a topic of a large number of other papers discussing properties of the compound - mostly biomedical.
A search in Google Scholar 'thapsigargin' will present with loads options for each flavor of secondary criterion. The point is the compound has lots of reports of interesting properties, which reduces the chances of this research note being a complete anomaly.
I would file it under the 'I hope that some day this has proven merit' section.
1 Copyright embargo: https://en.wikipedia.org/wiki/Embargo_(academic_publishing)
In academic publishing, an embargo is a period during which access to academic journals is not allowed to users who have not paid for access (or have access through their institution).
If anyone can see the original, please correct anything that I managed to mess up above.
-- truly unhelpful in this case. It limits what we can reasonably get from either article, although the pop sci article has hyperbole, IMO. Which you should probably ignore.