Why are non-coding genes called "genes"

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In summary, the conversation discusses the definition of a gene and how it applies to non-coding DNA sequences. It is mentioned that genes do not necessarily have to code for a specific trait and can also include non-coding control sequences that can influence gene expression. The conversation also touches on the estimated number of protein-coding genes in the human genome.
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I thought that a gene by definition is a unit of heredity, so a portion of DNA that doesn't code for anything wouldn't be a unit of heredity and therefore shouldn't really be called a gene, no? Also if current estimates for protein coding genes in human genome is about 20000, how many total genes are there in human genome?
thanks for any help
 
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Genes don't have to code for any thing to be a gene.
Gene is a term that has been used since before DNA was understood. It has been used to designate any inheritable trait.

Non-coding control sequences can be found as mutations (and therefore considered a gene) even though they do not code for proteins or RNA transcripts.
They could be binding sites for proteins which could control transcribing of a neighboring coding sequence.
 
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1. Why are non-coding genes called "genes"?

Non-coding genes are called "genes" because they are segments of DNA that contain genetic information and are passed down from parent to offspring, just like coding genes. Despite not coding for proteins, they still play important roles in regulating gene expression and controlling various biological processes.

2. What is the difference between coding and non-coding genes?

Coding genes, also known as protein-coding genes, are responsible for producing proteins that carry out specific functions in the body. Non-coding genes, on the other hand, do not code for proteins but instead have regulatory functions, such as controlling gene expression and cell development.

3. How many non-coding genes are there in the human genome?

It is estimated that the human genome contains approximately 20,000-25,000 protein-coding genes, but the number of non-coding genes is much larger, with some estimates reaching up to 100,000 or more. However, the exact number is still being studied and may vary depending on the definition of a non-coding gene.

4. Do non-coding genes have any biological functions?

Yes, non-coding genes have important biological functions, such as regulating gene expression, controlling cell differentiation and development, and maintaining the stability of the genome. They also play a role in diseases and disorders, such as cancer and genetic disorders.

5. How are non-coding genes studied and their functions determined?

Non-coding genes are studied through various techniques, such as DNA sequencing, gene expression analysis, and genetic manipulation. Scientists also use bioinformatics tools and databases to analyze non-coding DNA sequences and predict potential functions. Additionally, experiments using model organisms and cell cultures can provide insights into the functions of non-coding genes.

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