Newton's laws of motion can be directly applied to exercise, illustrating the relationship between force, mass, and acceleration. The first law, inertia, explains how a body at rest remains at rest until acted upon, relevant in exercises that require overcoming initial resistance. The second law emphasizes that the acceleration of an object is proportional to the net force acting on it, which is crucial in understanding how muscles generate force during movement. The third law highlights that for every action, there is an equal and opposite reaction, applicable in various exercises where forces interact, such as pushing against weights. Understanding these principles can clarify the energy dynamics in both dynamic and isometric exercises.