To calculate the average duration of a Snakes and Ladders game in terms of moves, one approach is to simulate the game using a computer program, though this method can be time-consuming and yield inaccurate results. An alternative method involves using probabilities by starting with a value of 1 on the first square and distributing values across subsequent squares based on die rolls, while accounting for snakes and ladders. This can be done iteratively, using a buffer to track movements and recording when players finish the game. For a single player, the average can be calculated by multiplying incoming values by the moves they arrive at, while a method exists for calculating averages in a two-player scenario as well. Overall, leveraging probability distributions can provide a more efficient way to determine average game duration.