The basic principle of clock synchronization is to ensure that the coordinate description of physics is as symmetric as the physics itself. For example, bullets shot off by the same gun at any point and in any direction should always have the same coordinate velocity dr/dt . Because of the light-postulate, photons serve particularly conveniently as such bullets in SR.
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We should, strictly speaking, differentiate between an inertial frame and an inertial coordinate system, although in sloppy practice one usually calls both IFs. An inertial frame is simply an infinite set of point particles sitting still in space relative to each other. For stability they could be connected by a lattice of rigid rods, but free-floating particles are preferable, since keeping constant distances from each other is also a criterion of the non-rotation of the frame. A standard inertial coordinate system is any set of Cartesian x,y,z axes laid over such an inertial frame, plus synchronized clocks sitting on all the particles, as described above. Standard coordinates always use identical units, say centimeters and seconds.