The discussion centers on the existence and interaction of mesons with matter, particularly in the context of matter-antimatter asymmetry stemming from the Big Bang. It highlights that while there was initially equal amounts of matter and antimatter, a slight excess of matter (about 1 part in 10^9) led to the current universe dominated by matter and photons. The asymmetry is partially attributed to CP violation, as observed in experiments like BaBar, which showed interactions between B and anti-B mesons resulting in stable matter. Mesons can occur naturally and interact with matter, especially under high-energy conditions typical of stars or radioactive decay, but they are not stable and have short lifetimes. Overall, the conversation reflects ongoing inquiries into fundamental questions in theoretical physics regarding the nature of matter and antimatter.