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So far the Delta variant has been largely contained to hotspots in the NW of England. The problem is that a general opening up would potentially unleash it across the whole country.
PeroK said:So far the Delta variant has been largely contained to hotspots in the NW of England. The problem is that a general opening up would potentially unleash it across the whole country.
AlexCaledin said:Interestingly, no significant difference in COVID-19 incidence was observed between previously infected and currently unvaccinated participants, previously infected and currently vaccinated participants, and previously uninfected and currently vaccinated participants.
The participants from these three groups exhibited a significantly lower incidence of SARS-CoV-2 infection compared to previously uninfected and currently unvaccinated participants.
https://www.news-medical.net/news/2...ID-19-Findings-of-Cleveland-Clinic-study.aspx
Background The purpose of this study was to evaluate the necessity of COVID-19 vaccination in persons previously infected with SARS-CoV-2.
Methods Employees of the Cleveland Clinic Health System working in Ohio on Dec 16, 2020, the day COVID-19 vaccination was started, were included. Any subject who tested positive for SARS-CoV-2 at least 42 days earlier was considered previously infected. One was considered vaccinated 14 days after receipt of the second dose of a SARS-CoV-2 mRNA vaccine. The cumulative incidence of SARS-CoV-2 infection over the next five months, among previously infected subjects who received the vaccine, was compared with those of previously infected subjects who remained unvaccinated, previously uninfected subjects who received the vaccine, and previously uninfected subjects who remained unvaccinated.
Results Among the 52238 included employees, 1359 (53%) of 2579 previously infected subjects remained unvaccinated, compared with 22777 (41%) of 49659 not previously infected. The cumulative incidence of SARS-CoV-2 infection remained almost zero among previously infected unvaccinated subjects, previously infected subjects who were vaccinated, and previously uninfected subjects who were vaccinated, compared with a steady increase in cumulative incidence among previously uninfected subjects who remained unvaccinated. Not one of the 1359 previously infected subjects who remained unvaccinated had a SARS-CoV-2 infection over the duration of the study. In a Cox proportional hazards regression model, after adjusting for the phase of the epidemic, vaccination was associated with a significantly lower risk of SARS-CoV-2 infection among those not previously infected (HR 0.031, 95% CI 0.015 to 0.061) but not among those previously infected (HR 0.313, 95% CI 0 to Infinity).
Conclusions Individuals who have had SARS-CoV-2 infection are unlikely to benefit from COVID-19 vaccination, and vaccines can be safely prioritized to those who have not been infected before.
Summary Cumulative incidence of COVID-19 was examined among 52238 employees in an American healthcare system. COVID-19 did not occur in anyone over the five months of the study among 2579 individuals previously infected with COVID-19, including 1359 who did not take the vaccine.
Background The degree to which infection with SARS-CoV-2 confers protection towards subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of-charge PCR-testing strategy, approximately 4 million individuals (69% of the population) underwent 10·6 million tests. Using these national PCR-test data from 2020, we estimated protection towards repeat infection with SARS-CoV-2.
Methods In this population-level observational study, we collected individual-level data on patients who had been tested in Denmark in 2020 from the Danish Microbiology Database and analysed infection rates during the second surge of the COVID-19 epidemic, from Sept 1 to Dec 31, 2020, by comparison of infection rates between individuals with positive and negative PCR tests during the first surge (March to May, 2020). For the main analysis, we excluded people who tested positive for the first time between the two surges and those who died before the second surge. We did an alternative cohort analysis, in which we compared infection rates throughout the year between those with and without a previous confirmed infection at least 3 months earlier, irrespective of date. We also investigated whether differences were found by age group, sex, and time since infection in the alternative cohort analysis. We calculated rate ratios (RRs) adjusted for potential confounders and estimated protection against repeat infection as 1 – RR.
Findings During the first surge (ie, before June, 2020), 533 381 people were tested, of whom 11 727 (2·20%) were PCR positive, and 525 339 were eligible for follow-up in the second surge, of whom 11 068 (2·11%) had tested positive during the first surge. Among eligible PCR-positive individuals from the first surge of the epidemic, 72 (0·65% [95% CI 0·51–0·82]) tested positive again during the second surge compared with 16 819 (3·27% [3·22–3·32]) of 514 271 who tested negative during the first surge (adjusted RR 0·195 [95% CI 0·155–0·246]). Protection against repeat infection was 80·5% (95% CI 75·4–84·5). The alternative cohort analysis gave similar estimates (adjusted RR 0·212 [0·179–0·251], estimated protection 78·8% [74·9–82·1]). In the alternative cohort analysis, among those aged 65 years and older, observed protection against repeat infection was 47·1% (95% CI 24·7–62·8). We found no difference in estimated protection against repeat infection by sex (male 78·4% [72·1–83·2] vs female 79·1% [73·9–83·3]) or evidence of waning protection over time (3–6 months of follow-up 79·3% [74·4–83·3] vs ≥7 months of follow-up 77·7% [70·9–82·9]).
Interpretation Our findings could inform decisions on which groups should be vaccinated and advocate for vaccination of previously infected individuals because natural protection, especially among older people, cannot be relied on.
I am of the same mind.atyy said:Interview with Christian Drosten
https://www.republik.ch/2021/06/05/herr-drosten-woher-kam-dieses-virus
[Excerpt translated from German by Google Translate]
Mr Drosten, in Germany you became the first source of information for many in this crisis with the NDR podcast “Coronavirus Update”. When you started the podcast over a year ago, what would you have liked to know what you know today?
I didn't know at the time how the media worked.
What do you mean by that?
What I didn't realize at all is this false balance that can arise in public, in the media. And that this can only be corrected to a limited extent.
False balance?
That one says: Okay, here is a majority opinion, which is represented by a hundred scientists. But then there are these two scientists who argue the opposite. In the media presentation, however, you then put one of these hundred against one of these two. And then it looks like it's 50:50, a conflict of opinion. And then what happens is what is actually the problem with it, namely that politicians say: "Well, then the truth will lie in the middle." That is that wrong compromise in the middle. And that's something I didn't know qualitatively. I didn't know this phenomenon existed. I also didn't know that it was so persistent and inevitable. This has happened in practically all countries, this problem. All scientists speak of it. It was not clear to me that a podcast would put me in the middle of this area of tension.
ChemAir said:100 scientists with one (scientifically determined) opinion vs 1 individual with anecdotally driven hyperbole with pictures is not pretty.
Media and politicians haven't helped this situation.
The fact that there is a ratio of 100:1 scientists promoting one way over another shouldn't have to be the only reason why I choose that way. The fact that I choose one way or the other doesn't also mean that I agree with the reasoning behind the scientists promoting it (whether they are 100 or just 2). I might choose that way for entirely different reasons.chemisttree said:Believing the 100 scientists and not the two in the minority because of majority rule IS NOT SCIENCE!
The arguments on both sides must be at least discussed and not suppressed.
It depends what you mean by suppressed. Anyone can call themselves a scientist and promote a bizarre theory. Do we give all points of view equal airtime?chemisttree said:Believing the 100 scientists and not the two in the minority because of majority rule IS NOT SCIENCE!
The arguments on both sides must be at least discussed and not suppressed.
Context matters. Most here will not claim that arguments and ideas should be suppressed in the advancement of science, but when it comes to the media, fringe ideas shouldn't be given the appearance of equal weight to the view accepted by the mainstream.chemisttree said:Believing the 100 scientists and not the two in the minority because of majority rule IS NOT SCIENCE!
The arguments on both sides must be at least discussed and not suppressed.
You are missing the context. That was about inaccurate and misleading media coverage of science, not about science itself. Nobody is saying that the 2 scientists need to stop doing their science, but there is little value and no truth in disproportionately inflating their media coverage.chemisttree said:Believing the 100 scientists and not the two in the minority because of majority rule IS NOT SCIENCE!
The arguments on both sides must be at least discussed and not suppressed.
To do that properly requires subject-specific expertise. We cannot expect people to be an expert in everything. At best we can show what experts say. If you give some random crackpot or fringe scientist the same air time as the consensus of all experts then viewers/readers will get the impression there would be an actual scientific discussion without a clear favorite, which is often wrong.jack action said:Isn't it up to the readers of those reports to make up their minds?
No, it doesn't. You don't have to understand how a car works to hire a mechanic. You ask some questions to different mechanics and you determine who looks more trustworthy. Sometimes it's the stranger with the big diploma and years of experience, sometimes it's your brother-in-law. People have been doing this for hundreds of years, if not thousands.mfb said:To do that properly requires subject-specific expertise.
My humble opinion is, that 'these people' risks far more than the scientific community. The conflict arises when they endanger others, or when they expected to be saved even against the consequences of their behaviour.jack action said:if the scientific community is too arrogant towards these people instead of trying to earn their trust back, it can lose everything.
A bunch of security cams could 'report' too but that does not nominate them for Nobel. Sorry.jack action said:I don't understand why there should be a consensus. Isn't science only there to report observations?
If there is (scientific) argument then you are right. But 'media' as-is is not really about any kind of respectable arguments.chemisttree said:The arguments on both sides must be at least discussed and not suppressed.
to be trusted - making basic mistakes no scientist would make. https://www.spiegel.de/internationa...summer-a-f22c0495-5257-426e-bddc-c6082d6434d5
In terms of COVID for the UK daily updates using the experts was a mixture of layman’s language describing the illness risks, real data, graphs, diagrams etc.jack action said:No, it doesn't. You don't have to understand how a car works to hire a mechanic. You ask some questions to different mechanics and you determine who looks more trustworthy. Sometimes it's the stranger with the big diploma and years of experience, sometimes it's your brother-in-law. People have been doing this for hundreds of years, if not thousands.
And this is the problem with the scientific community right now: They're slowly losing the trust of the general population. Why does a basketball player begin to publicly claim that the Earth is flat? Does he really care about the shape of the Earth? No, he doesn't. Why do people listening to him would believe him? He has zero credibility and he's just throwing the idea in a press conference, with no evidence to support it; people are not stupid, they can see that.
The true message here is that more and more people don't trust anything coming from the scientific community and that's how they retaliate, by throwing everything out the window. They will not answer back to you with your words and methods: they don't understand it, they don't even trust it. Just like when your mechanic or your brother-in-law says something fishy: you stop listening to him and go somewhere else; you don't care about his credentials.
And if the scientific community is too arrogant towards these people instead of trying to earn their trust back, it can lose everything. Even if it has all the right answers.
Yeah, maybe it is not a good idea for the scientific community to let the government and the media control their message. Maybe it is not a good idea to accept money from the government too.pinball1970 said:I think the back lash against the science in the UK is partly to do with anti-government sentiment so the rest follows.
The briefings had to be a mixture of minsters and scientists as the policy goes on the back of it.jack action said:Yeah, maybe it is not a good idea for the scientific community to let the government and the media control their message. Maybe it is not a good idea to accept money from the government too.
You would think flat Earth, magnetic vaccines, Jewish space lasers & co would be in that category, but apparently they are not.jack action said:Just like when your mechanic or your brother-in-law says something fishy: you stop listening to him and go somewhere else; you don't care about his credentials.
Should I start a Gofundme for the LHC and SuperKEKB?jack action said:Maybe it is not a good idea to accept money from the government too.
That doesn't work here/is backwards. The pandemic response is coordinate by the government(s). The scientists are advising the government(s) on how to run the response. The government(s) pay the scientists for their advice/expertise. There's just no way around that here. The problem @pinball1970 pointed out is accurate: the distrust extends from anti-government sentiment to the scientists employed by the government (with the ironic twist in the US that POTUS was stoking that sentiment).jack action said:Yeah, maybe it is not a good idea for the scientific community to let the government and the media control their message. Maybe it is not a good idea to accept money from the government too.
Seriously?You don't have to understand how a car works to hire a mechanic. You ask some questions to different mechanics and you determine who looks more trustworthy. Sometimes it's the stranger with the big diploma and years of experience, sometimes it's your brother-in-law. People have been doing this for hundreds of years, if not thousands.
If you read what I wrote carefully, you should understand that those people are not approving claims, they are really dismissing people they don't trust.mfb said:If people could easily assess how credible claims are - as you claim - then all the nonsense wouldn't get any attention because people would dismiss it directly.
No, what falls into this category are all the scary predictions that never happened or other exaggerations that were presumably backed by science (for example, statements done in nutrition come to mind). Those are the fishy statements I'm referring to.mfb said:You would think flat Earth, magnetic vaccines, Jewish space lasers & co would be in that category, but apparently they are not.
Why not? A lot of religions don't get funded by the government. The Crazy Horse memorial is not government-funded. Was Issac Newton's work funded by the government? Why wouldn't you find enough people believing in science to get funds? Don't despair, @pinball1970 would be happy to contribute:mfb said:Should I start a Gofundme for the LHC and SuperKEKB?
I would too. See, you don't need the government as a middle-man. Except if you want money from people who don't want to give it to you.pinball1970 said:My taxes fund some government scientific research projects, I am happy my money is spent in this way.
I agree with that 100% and it is exactly what I said. The message to be heard is not "I believe vaccination is wrong" but "I don't trust you anymore, no matter what you say". I also understand that governments and media not always represent the scientist's findings as they were presented, but more as what message they want to pass on.russ_watters said:the distrust extends from anti-government sentiment, to the scientists employed by the government
Do you mean like that? Do you know why you did that? That's because you cannot trust a mechanic alone, just because he's a mechanic. You need to discuss with people who had experiences. Sometimes people who just had experiences with mechanics and no knowledge of car repair are helpful too. You do the same with doctors and you would be crazy not to do it.russ_watters said:When you "ask some questions to different mechanics", that means going to different auto shops and asking people you know are actual mechanics, not just some random dood on Reddit what that rattle might be. I mean, maybe you do that too, but if you think there's a legitimate problem you take your car to a legitimate mechanic.
You mean more serious than a braking system? You can kill yourself or others with a car that is not correctly maintained.russ_watters said:Medicine is different/more serious/more complicated.
Still not convinced of that. If you don't want to get Covid, take the measures you think are appropriate. You think wearing a mask is sufficient? Wear a mask. You think you're OK with a vaccine? Get vaccinated. Too many "irresponsible" people outside without a mask? Stay at home. Get a positive pressure set up for your home if you think you need it. I don't care where you get your information to do your risk analysis. And I welcome the government giving me information to help me make the best decisions. Still, I think it is my decision.russ_watters said:COVID is not just an individual risk, it is a societal one,
The problem arises if you, not understanding how the car works, hire a good mechanic and then refuse to let him fix your brakes when he, as an expert, tells you that the brakes are unsafe but you read on facebook that mechanics disagree about the importance of fixing your brakes. Then you go out and endanger your own life and the lives of others simply because you, having no understanding, put your judgement over that of the experts.jack action said:You don't have to understand how a car works to hire a mechanic.
This is not a problem specific to the scientific community. Trust in all institutions is eroding among the general population. That includes government, financial institutions, religion, education, marriage, police, military, democracy, and science. I suspect that science is actually faring better than most other institutions as part of this general decline in institutional trust, but I don't have a reference for that.jack action said:And this is the problem with the scientific community right now: They're slowly losing the trust of the general population.
No, it's not what you said or what I said; you cut out the thesis what you quoted. Again: the government employs the scientists and delivers the scientists' message. That's exactly the opposite of what you said, but it is the unavoidable reality here.jack action said:I agree with that 100% and it is exactly what I said.
That's a problem. Once someone shuts out The Authority, then they have primed themselves to do the opposite of what The Authority suggests/demands, regardless of merit. That's basically what has happened here.jack action said:The message to be heard is not "I believe vaccination is wrong" but "I don't trust you anymore, no matter what you say".
No, you're misrepresenting the issue here/there. For starters, I'm a mechanical engineer and have some knowledge of how cars and their systems operate. So are many on PF (including you I believe?). I didn't take the car to a mechanic yet not because I don't trust them, but because the issue is minor enough I don't need to yet. Nor is that an accurate portrayal of dissenting information, particular given PF's high quality standards and members. Members here have known expertise. I repeat: much of thejack action said:Do you mean like that? Do you know why you did that? That's because you cannot trust a mechanic alone, just because he's a mechanic.
In point of fact, that is expressly prohibited on PF, for exactly the reasons I've explained. The approach that is being taken by many on this subject is not just dangerous, but is indeed in many cases, crazy. No, I most certainly would not take the same approach with doctors as I did with my car issue.jack action said:You do the same with doctors and you would be crazy not to do it.
Yes, much more serious than a braking system. I can kill a small number of people with a failed braking system, but I can't kill 600,000. And much more complicated than a braking system.jack action said:You mean more serious than a braking system? You can kill yourself or others with a car that is not correctly maintained.
That's an unreasonably exclusivist view of how freedom works, because the choices are not symmetrical. One person can decide for everyone else in a supermarket/bar/stadium if that venue has a COVID risk, forcing everyone else to take action to mitigate it. Worse, nobody knows who/if that risk exists. It's similar to smoking, except you can't smell it. Prior to about 20 years ago, one smoker could go to a bar and turn the bar into a "smoking bar", that affected people who were already there. Heck, you could even say the same for drunk driving; if you don't want to be around me while I'm driving drunk, maybe you should stay home? The freedom to act irresponsibly ends where it impacts someone else. This is a foundational philosophy of why/for what modern governments exist.jack action said:Still not convinced of that. If you don't want to get Covid, take the measures you think are appropriate. You think wearing a mask is sufficient? Wear a mask. You think you're OK with a vaccine? Get vaccinated. Too many "irresponsible" people outside without a mask? Stay at home. Get a positive pressure set up for your home if you think you need it. I don't care where you get your information to do your risk analysis. And I welcome the government giving me information to help me make the best decisions. Still, I think it is my decision.
[edit] That's an example of a mitigation effort. This discussion isn't about how an individual's mitigation effort doesn't affect anyone else, it's about how an individual's lack of mitigation does affect everyone else. You're arguing the inverse of the position you are trying to defend.jack action said:Survivalists have been doing this type of thing for many years and they don't wait for the government or other people around them to act.
And, indeed, you can be arrested and charged with vehicular homicide for failure to maintain a vehicle:Dale said:The problem arises if you, not understanding how the car works, hire a good mechanic and then refuse to let him fix your brakes when he, as an expert, tells you that the brakes are unsafe but you read on facebook that mechanics disagree about the importance of fixing your brakes. Then you go out and endanger your own life and the lives of others simply because you, having no understanding, put your judgement over that of the experts.
Or the distinction between liberty and anarchy.russ_watters said:The freedom to act irresponsibly ends where it impacts someone else. This is a foundational philosophy of why/for what modern governments exist.
And, after all, the US Constitution says (emphasis mine):Dale said:Or the distinction between liberty and anarchy.
jack action said:No, it doesn't. You don't have to understand how a car works to hire a mechanic. You ask some questions to different mechanics and you determine who looks more trustworthy. Sometimes it's the stranger with the big diploma and years of experience, sometimes it's your brother-in-law. People have been doing this for hundreds of years, if not thousands.
And this is the problem with the scientific community right now: They're slowly losing the trust of the general population. Why does a basketball player begin to publicly claim that the Earth is flat? Does he really care about the shape of the Earth? No, he doesn't. Why do people listening to him would believe him? He has zero credibility and he's just throwing the idea in a press conference, with no evidence to support it; people are not stupid, they can see that.
The true message here is that more and more people don't trust anything coming from the scientific community and that's how they retaliate, by throwing everything out the window. They will not answer back to you with your words and methods: they don't understand it, they don't even trust it. Just like when your mechanic or your brother-in-law says something fishy: you stop listening to him and go somewhere else; you don't care about his credentials.
And if the scientific community is too arrogant towards these people instead of trying to earn their trust back, it can lose everything. Even if it has all the right answers.
Maybe it's stable, but 44% is not a lot to begin with. Anyway, not for someone like me who is a true believer in the scientific method. But thanks for the data.Ygggdrasil said:I don't think the specific point about scientists losing the trust of the general public is true. In general, polling in the US shows that public confidence in scientists has remained stable for decades,
The real question is why do these news sources choose to report those reporting conflicts in the first place. And this brings me back to the point that people are beginning to lose their trust in their usual sources.Ygggdrasil said:Many news sources focus on reporting conflict and as such they magnify the voices of the minority who are doubting scientific results.
It sells better.jack action said:The real question is why do these news sources choose to report those reporting conflicts in the first place.