turbo-1 said:
Consider that the genetic code shared by chimps and humans is huge compared to the differences. Yet the differences in outcome is pretty darned significant. How is a computer simulation supposed to evaluate such differences, especially in organisms that it has no information on apart from relic DNA?
The first step would be to simulate the life cycles of known organisms from their known genomes based on observing how nature actually works. Maybe more information will be needed to do this than just an organism's genome, but any such information should be readily available to us in time. As I said before, we are only just now beginning to simulate how proteins are made from DNA. Do you have some reason to think that there is a limit to how far biotechnology can go beyond this, short of simulating the complete life cycle of an organism, given the current exponential trends in advancing biotechnology and computing power?
I am currently reading Ray Kurzweil's book
The Singularity is Near, and that is where some of these ideas are coming from.
I can't for the life of me imagine how the computer simulation might account for the differentiation of the beak morphology (and crossover characteristics) in the Galapagos finches, much less start reconstructing the genomes of creatures that are no longer extant.
We would begin by sampling the DNA of these various finches, and then run simulations of their life cycles based on their genomes, and see if the simulations accurately reproduce the observed differences between the finches. If the simulations are flawed, then they aren't ready for general use. However, if the simulations are not flawed, then we can use them with confidence to simulate other creatures based on hypothetical genomes.
zoobyshoe said:
To the extent you have to take any individual species' environment into consideration, don't you have to know the genomes, and life cycles of every plant and insect and microbe it would have encountered? In other words, to be sure of your accuracy you'd have to be working back from a sort of onmiscience about the present, which we don't have, and take everything back all together step by step. To do it for one species you'd have to do it for all, and you'd also have to do it for the Earth's weather and climate.
Not necessarily. Consider these eleven species:
http://hometown.aol.com/darwinpage/whale1.gif
We have apparently deduced that there is an evolutionary progression between these species. No doubt, if we compared the genomes of these species we would find a pattern that is consistent with this progression.
All that I am suggesting here is that in the future biotechnology and computing power will be far more capable, and that interpolating between these known genomes may be possible. We could probably do some creative gene splicing and actually grow these experimental creatures in a lab, but simulations seem both more humane and more practical to me.