'Proposition' is a more precise term than 'statement'. Propositions are always statements, but it's a matter of interpretation whether the converse is true. If I hurt my foot and say 'Ow!' that is not a proposition and some would call that a statement but others wouldn't. If you want to avoid ambiguity, use the word 'proposition'.
When people say a sequence of written symbols or a vocal utterance is meaningless, they usually mean that it appears to be intended to be a proposition, but it does not qualify as a proposition, typically because it contains a syntactic error.
With that interpretation, '4+1' is not a meaningless statement because it is clearly not intended to be a proposition. An example of a meaningless statement would be '##4+1\times=3##'. This is meaningless because it contains a syntactic error - the multiplication symbol is missing one of its arguments.
Some people also say that attempted propositions can be meaningless because of semantic errors. But others say that those statements are meaningful but evaluate to false. The classic example is Bertrand Russell's 'The present king of France is bald'. Some say this is meaningless because France currently has no king. But Russell gives an interesting way of analysing the sentence, bringing out the hidden assumptions, so that it evaluates to false.