There is research going on in the field of mesoscopic transport, the regime were electronic devices get so small that quantum mechanical effects need to be considered, together with the well understood classical laws of electronics. Theoretically, it could lead to transistors far smaller than they are now and could operate with a single electron.
At my university, there is a group doing research on the physics in this regime. The professor even wrote a book about it:
https://www.amazon.com/dp/3527409327/?tag=pfamazon01-20
Really interesting stuff.