All quark and lepton masses are free parameters in the Standard Model. There have certainly been many attempts to explain them with a more fundamental theory. People have constructed models that could explain various features of the observed particle spectrum, and some of those models are consistent with all known data, and hence could be true. However, since we have no positive evidence for physics beyond the Standard Model, this is all in the realm of speculation. The good news is that many models of this type are testable at the upcoming collider - the LHC. So, hopefully we'll soon have some more experimental insight into this question.