How can I accurately calculate the heat transfer coefficient for my bioreactor?

[a20792]

Need help to find the heat transfer coefficient for a stirred bioreactor any help on how do I go about...

 

[Driftwood1]

Need help to find the heat transfer coefficient for a stirred bioreactor any help on how do I go about...

Is this a jacketed or coiled vessel?

...the overall heat transfer coefficient not only depends on the heat exchanger configuration and on the choice of coolant, it also depends on the fermentation fluid, its fouling potential and its degree of mixing.

the overall heat transfer coefficient needs to be determined

The dimensionless groups Reynolds, Prandtl and Nusselt numbers are relevant to this problem

Bioreactors can get very complex because as the fermentation proceeds with time, fouling can increase and the physical properties of the fluid can change (such viscosity)

If you are designing a bioreactor form scratch then these factors should be considered otherwise you may end up with an underdesigned (or overdesigned) reactor.

 

[a20792]

Is this a jacketed or coiled vessel?

...the overall heat transfer coefficient not only depends on the heat exchanger configuration and on the choice of coolant, it also depends on the fermentation fluid, its fouling potential and its degree of mixing.

the overall heat transfer coefficient needs to be determined

The dimensionless groups Reynolds, Prandtl and Nusselt numbers are relevant to this problem

Bioreactors can get very complex because as the fermentation proceeds with time, fouling can increase and the physical properties of the fluid can change (such viscosity)

If you are designing a bioreactor form scratch then these factors should be considered otherwise you may end up with an underdesigned (or overdesigned) reactor.

its a jacketed vessel...
I've already got a correlation, do I simply plug in the numbers and get a value for the heat transfer coefficient or are there other things are consider?

 

[Driftwood1]

its a jacketed vessel...
I've already got a correlation, do I simply plug in the numbers and get a value for the heat transfer coefficient or are there other things are consider?

Is your correlation specific to your particular process conditions?

Some correlations simply reflect the reactor design and make many assumptions as to what fluids are used and what sort of fouling occurs. (rheology etc)

Have you crunched any numbers with the correlation you have?

Is this an existing bioreactor that has laready been built?

Or are you in the design phase?

You need as much information, process data and fluid properties etc as you can get.

Nowadays complex systems are modeled with numerical analysis.