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enceladus

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In a pharmaceutical lab,a certain pressure is applied to IV bags using the equipment shown below.We need to calculate the force acting on the bags based on the applied pressure.I know the formula is F=PxA.But i am not sure what the surface area is.Should i take the whole surface area of the empty bag or the part of the bag where the upper plate touches the bag or something else?The container is not completely filled with liquid.There is air above liquid.How does the compressed air affect the result?