It is indeed possible to have one major and two minors at many colleges, including options like majoring in physics while minoring in math and biochemistry, or vice versa. Students must complete the necessary requirements for both minors, which may involve taking more classes than required for a major. While some may view this as excessive, having a diverse transcript can be beneficial for graduate school applications. The choice of major and minors should align with personal interests and career aspirations, and students are encouraged to consult academic advisors to manage their course load effectively and ensure they can handle the demands of their chosen path. Additionally, it's essential to verify that the desired minors, such as biochemistry, are offered at the institution.