It's quantum mechanics doesn't mix well with general relativity. Special relativistic quantum mechanics is a perfectly well defined field.
They don't mix well because nobody has as yet been able to coherently combine them. The two theories describe different things. One describes gravity (general relativity), and the other describes the other 3 forces of nature. Roughly speaking, nobody has been able to straightforwardly combine the two in a way that does not give you a bunch of infinities everywhere.
There are some attempts like string theory, and loop quantum gravity, but they are basically wholly new theories, and they all contain parts that have not yet been worked out.