In most practical pipes for everyday use, the flow is primarily turbulent. The kinetic energy would just be 1/2 m*v^2, where m is the mass of a section of fluid in the pipe and v is the velocity of that fluid where you picked it.
Turbulent kinetic energy is particularly useful when looking at CFD turbulence models. For example, the very standard k-ε model uses turbulent kinetic energy as one of the "transported" variables representing the turbulent properties.
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