What activates protein synthesis?

[jayadds]

Hi all,

I was just wondering, what stimulus activates protein synthesis? I already know the steps of protein synthesis but is there a particular mechanism that triggers the RNA polymerase to start transcription? In other words, how does the body know when to produce proteins? Is it possibly with hormones?

Many thanks,
Jay

 

[Ryan_m_b]

Protein synthesis is controlled by transcription factors that bind to DNA to either promote or repress transcription.

 

[Ygggdrasil]

Here's a chapter from Albert's Molecular Biology of the Cell giving some examples of how various signals can turn genes on and off in bacteria and eukaryotes:

https://www.ncbi.nlm.nih.gov/books/NBK26872/