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jaumzaum
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I know that in prokaryotes primers are removed by a combination of RNAse-H and DNA Polimerase I, but who does that in eukaryotes?
What enzyme removes the primer in EUKARYOTES
- Thread starter jaumzaum
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SUMMARY
In eukaryotes, the removal of RNA primers during DNA replication is primarily facilitated by the enzyme RNase H, along with the action of DNA polymerase δ (delta). This process is crucial for ensuring the integrity of the lagging strand synthesis. The combination of these enzymes allows for the replacement of RNA primers with DNA, thereby maintaining the fidelity of the genetic material during cell division.
PREREQUISITES- Understanding of eukaryotic DNA replication mechanisms
- Familiarity with the roles of RNase H and DNA polymerases
- Knowledge of lagging strand synthesis
- Basic concepts of molecular biology and enzymatic functions
- Research the specific functions of DNA polymerase δ in eukaryotic cells
- Explore the mechanisms of RNA primer removal in prokaryotes for comparison
- Investigate the implications of primer removal on DNA replication fidelity
- Learn about other enzymes involved in DNA replication and their interactions
Molecular biologists, geneticists, and students studying eukaryotic cell biology will benefit from this discussion, particularly those interested in DNA replication processes and enzymatic functions.
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