What is acet in organic chemistry?

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Discussion Overview

The discussion revolves around the term "acet" in organic chemistry, specifically its application in the names of compounds like acetophenone and acetic acid. Participants explore the significance of the acetyl group and its role in nomenclature and biological processes.

Discussion Character

  • Conceptual clarification
  • Technical explanation

Main Points Raised

  • Some participants inquire about the meaning of "acet" and its relevance in the names of certain compounds.
  • One participant suggests that CH3CO represents the acetyl group but seeks clarification on its standard nomenclature usage.
  • Another participant describes the acetyl radical as a CH3-(C=O)-R group, noting that this terminology is not part of standard IUPAC nomenclature and is primarily used as common names.
  • There is mention of the biological importance of acetyl groups, including their generation from pyruvate and their role in metabolic processes such as fatty acid biosynthesis and protein acetylation.

Areas of Agreement / Disagreement

Participants express curiosity and provide insights into the term "acet," but there is no consensus on a formal definition or standard nomenclature rules. The discussion includes both technical details and biological implications without resolving the nomenclature question.

Contextual Notes

The discussion highlights the informal nature of naming conventions related to acetyl groups and the lack of formal rules in IUPAC nomenclature. There are also unresolved aspects regarding the standardization of nomenclature in organic chemistry.

Logic hunter
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What does it mean and why do acetophenone and acetic acid have it in their name ?
 
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Think about it for just a moment.
 
Bystander said:
Think about it for just a moment.
CH3CO, as I guessed but how do you use it in nomenclature in a standard way.
 
Yes, a CH3-(C=O)-R group is commonly referred to as an acetyl radical. Note that this is not standard IUPAC nomenclature, so names using the root acetyl are mostly common names for compounds and there are no formal rules for its use in the names of compounds.

The acetyl group is particularly important in various aspects of biology. Acetyl groups can be generated from pyruvate, the end product of glycolysis. Decarboxylation of pyruvate transfers an acetyl radical from pyruvate to a vitamin called coenzyme A (CoA), and the acetyl group from the resulting acetyl-CoA molecule can then be transferred to other substrates or used as a building block for other metabolic processes (such as fatty acid biosynthesis). One important acetylation reaction is the transfer of the acetyl group from coenzyme A to lysine residues in proteins. Acetylation of the histone proteins that help wrap and package DNA is thought to be very important for regulating gene expression and other biological processes involving DNA.
 
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